Complexo SNARE e a fusão das vesículas de acetilcolin

Há um artigo com boas imagens sobre o complexo SNARE aqui:

http://www.nature.com/articles/srep04575

Uma das imagens é essa:

Cuja legenda segue:

The model of the stimulatory SNARE zippering by Syt1 and Ca21. In this model, syntaxin-1A (red) and SNAP-25 (green) pre-assemble int0 the binary t-SNARE complex at plasma membrane, while VAMP2 (blue) and Syt1 (pink) are anchored on the vesicle membrane. In the stage of vesicle docking, Syt1 binding to the binary t-SNARE complex facilitates the synaptic vesicle docking with the plasma membrane53,54. The N-terminus of the binary t-SNARE complex then start zippering with the N-terminus of VAMP2, and form into a partially zipped trans SNARE complex. Upon the rise of the Ca21 level Syt1-Ca21 interacts with the partially zipped complex and facilitates the SNARE zippering at membrane proximal region, which drives the vesicle fusion.